European Advanced Specialization Course
LONGEVITY MEDICINE
Foundations for professional practice.
[MDs ONLY]
The Specialization Course in Longevity Medicine is a premier training program, specifically designed for medical professionals who wish to integrate the most advanced knowledge of biology and clinical practice to promote healthy longevity into their daily practice. The goal is to qualify the professional figure of the Longevity MD Specialist by providing comprehensive diagnostic and therapeutic training, focused on early diagnosis, prevention of chronic non-communicable diseases, treatment of processes related to cellular senescence, and the restoration of the patient’s biological balance and physiological capabilities.
The course is divided into two sequential and independent modules, each of which culminates in a final exam that guarantees the acquisition of training credits. Access to Module 2 (Therapies) is strictly linked to passing the Module 1 (Diagnostics) exam, thus ensuring rigorous educational progression based on solid scientific foundations.
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Two independent and coordinated modules
Module 1: Longevity Medicine Diagnostics
| Main Topics | Lecturers | |
| 1. Introduction to Longevity Medicine | 1 Teaching Hours | |
| Definition and objectives of longevity medicine. The importance of a multidisciplinary approach. A brief historical overview and recent developments. | Prof. Alberto Beretta | |
| 2. The biological foundations of aging | 5 Teaching Hours | |
| The milestones of aging | Prof. Pedro Bastos | |
| The metabolic pathways of longevity | Prof. Fabio Sallustio | |
| Genetics of longevity | Prof. Paolo Garagnani | |
| Immunosenescence | Prof. Andrea Cossarizza | |
| 3. Human physiology and aging | 21 Teaching Hours | |
| Cardiovascular pathophysiology for longevity: from atherogenesis to risk management | Dr. Nicola Triglione | |
| Neurological physiology: cognitive decline, neuroplasticity and age-related pathologies | Prof.ssa Daniela Perani | |
| Respiratory Physiology: Abnormalities in lung function and respiratory capacity. | Prof. Nicola Scichilone | |
| Musculoskeletal physiology: sarcopenia, osteopenia and changes in strength, muscle mass and bone density | ||
| Metabolic physiology: changes in the metabolism of glucose, lipids and proteins | Prof Saverio Cinti | |
| Physiology of the reproductive system: age-related changes in the female reproductive systems | Prof.ssa Rossella Nappi | |
| Physiology of the reproductive system: age-related changes in the male reproductive systems | Dr. Alberto Gheza | |
| Cognitive domains: impact of aging on attention, memory, language, executive functions and visuospatial abilities |
Prof.ssa Francesca Baglio
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| Sense organs: the eye | Dr. Stefano Barabino | |
| Sense organs: the ears | ||
| Physiology of the skin | Prof.ssa Stefania Guida | |
| 4. Biological markers of aging | 11 Teaching Hours | |
| Genetics: analysis of the genetic profile and predisposition to age-related diseases | Phd. Davide Cacchiarelli | |
| Epigenetics: study of epigenetic modifications and their role in aging | Prof. Paolo Garagnani | |
| Role of proteomics in precision medicine | Phd Austin Argentieri | |
| Microbiome: assessment of microbiota composition and its influence on health and longevity | Prof. Enrico Bevacqua | |
| Blood chemistry: “non-canonical” parameters and interpretive ranges. | Dr. Giuseppe Cardillo | |
| Assessment of immunosenescence: new paradigms | Prof. Andrea Cossarizza | |
| Assessing inflammaging: new paradigms | Prof. Claudio Franceschi | |
| Assessment of mitochondrial function | Dr.ssa Chiara Macchi | |
| 5. Physiological markers of aging | 8 Teaching Hours | |
| Electrocardiogram (ECG) and cardiopulmonary exercise test (CPET) | Prof. Marco Vecchiato | |
| Spirometry and heart rate variability (HRV) | Prof. Stefano Palermi | |
| Body composition analysis: assessment of muscle, fat and bone mass | Dr. Alberto Cerasari | |
| Technologies, cognitive function assessment tests and cognitive stimulation |
Prof. Giuseppe Iannoccari
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| The contribution of “neuroimaging” to the study of brain plasticity | Prof.ssa Daniela Perani | |
| Wearable biomarkers and longevity medicine | Dr. Nicola Triglione | |
| 6. Orientation to the use of imaging technologies | 3 Teaching Hours | |
| Magnetic Resonance Imaging (MRI): Structural and functional assessment of organs. – Photon-counting CT scan | ||
| * Ultrasound: Dynamic imaging and assessment of soft tissues and blood vessels. | ||
| * Computed Tomography (CT): Imaging of bone structures and internal tissues. |
Module 2: Longevity Medicine Therapies
Reserved for physicians who have completed Module 1, this course focuses on therapeutic strategies and intervention techniques to modulate the aging process, influence individual risk profiles, and promote the enhancement of the patient’s physiological and cognitive reserve.
| Main Topics | Lecturers | |
| 1. Longevity Medicine Interventions | 31 Teaching Hours | |
| From personalized nutrition to precision nutrition: overview | Prof.ssa Hellas Cena | |
| Precision nutrition – omics sciences | PHD Maria Vittoria Conti | |
| Nutritional requirements and supplementation | PHD Nagaia Madini | |
| Over- and undernutrition in aging: diagnostics | PHD Nagaia Madini | |
| Nutrition and supplementation in obesity and metabolic risk | PHD Nagaia Madini | |
| Nutrition and supplementation in cardiovascular risk | PHD Cecilia Ricciardi Rizzo | |
| Nutrition and supplementation in neurodegenerative risk | PHD Rachele De Giuseppe | |
| Caloric restriction and mechanisms | Prof.ssa Hellas Cena | |
| Therapeutic physical activity: training models and physiological targets | Prof. Silvano Zanuso | |
| Respiratory Capacity Rehabilitation: Techniques and protocols to improve respiratory efficiency. | Dario Morelli | |
| Stress management and sleep quality. | Prof. Ugo Faraguna | |
| Longevity Pharmacology | ||
| Metabolism and obesity (GLP-1, dual agonists, etc.) | Prof. Paolo Fiorina | |
| Cardiovascular (ASA, statins, ezetimibe, bempedoic acid, monoclonal antibodies) | Dr. Nicola Triglione | |
| Molecules of the future (rapamycin, peptides, etc.) | Dr. Valerio Solari | |
| Hormone Replacement Therapy – Women | Prof.ssa Rossella Nappi | |
| Hormone Replacement Therapy – Men | Prof. Mario Rotondi | |
| Regenerative Medicine | ||
| Peptides: Role in tissue repair and in the modulation of biological processes. | ||
| Plasmapheresis: Potential applications in the removal of pro-aging factors. | Dr.ssa Maria Stigliano | |
| Mesenchymal Stem Cells: Mechanisms of action and therapeutic applications. | Dr. Eugenio Caradonna | |
| Platelet-Rich Plasma (PRP): Use in tissue regeneration and modulation of inflammation. | Dr. Eugenio Caradonna | |
| Biohacking Technology | ||
| Photobiomodulation: Biological effects of light and its applications. | Prof. Paolo Capodaglio | |
| Cold Technologies (Cryotherapy): Physiological responses and potential benefits. | Prof. Paolo Capodaglio | |
| Ozone Therapy: Mechanisms of action and controversial applications. | Dr. Claudio Tavera | |
| Infusion Therapies: Use of nutrients and drugs to optimize health. | Dr.ssa Roberta Costanzo | |
| Hypoxia/Hyperoxia: Oxygen modulation to induce adaptive responses. | ||
| Hyperbaric Oxygen Therapy: Applications and mechanisms. | Prof. Paolo Capodaglio | |
| Molecular Hydrogen: Potential antioxidant and anti-inflammatory effects. | ||
| Transcranial magnetic stimulation | Dr. Livio Luzi | |
| 2. Clinical Applications of Longevity Medicine: | 4 Teaching Hours | |
| Analysis of morbidity in the elderly population. | Prof.ssa Virginia Boccardi | |
| Discriminating criteria for screening algorithms for the main non-communicable chronic diseases (e.g., cardiovascular, neurodegenerative, metabolic, oncological). | Apollo Group | |
| Use of AI in the Clinical Setting: | Luca Bianchi | |
| Applications of artificial intelligence for early diagnosis. | Luca Bianchi | |
| AI for treatment personalization and outcome prediction. | Luca Bianchi | |
| AI-based decision support systems. | Luca Bianchi | |
| 3. Ethical and Social Aspects of Longevity Medicine: | 2 Teaching Hours | |
| Regulatory approach to the use of therapeutic technologies | ||
| Implications for public health and healthcare systems. | ||
| Considerations on equity and access to therapies. | ||
| Ethical debates on life extension. | ||
| 4. Professional paradigm shift | 3 Teaching Hours | |
| Medical history and ethical-professional approach in longevity medicine: from disease to prevention to enhancement medicine | Dr. Alberto Cerasari | |
| Patient engagement techniques | Dr. Filippo Ongaro | |
| Psychology and motivation of the healthcare professional | Dr.ssa Elena Mazza | |
| 5. Internship in Longevity Clinics (optional) | 80 Clinic Internship |
Training Credits and Requirements
Successful completion of each module will grant students 30 education training credits (CFU/ECTS), conditional on passing each module exam, essential for professional advancement and ongoing training as a doctor.
the training credit certification platform is the one managed and administered by the ECM Office of the University of Pavia,
The sequential nature of the modules ensures that each participant has a complete diagnostic background before tackling the most advanced therapeutic strategies.
The requirements for students to enroll are as follows:
Single-Cycle Master’s Degree in Medicine and Surgery (LM-41) all disciplines
How to participate and how to deliver the course
The course will be delivered in English and in asynchronous mode using the ECM platform https://www.ecmunipv.it/
Student access is managed via personal, non-transferable credentials provided at the time of registration.
Each course includes:
- asynchronous video lesson
- presentation deck of the lesson
- exercise
At the end of each training module, students take a competences skills certification exam delivered through the platform. Successful completion of the exam allows for the issuance of a certificate of training credits.
The Longevity MD Specialist qualification requires the completion of both training modules and passing the related exams.
Without prejudice to the student’s freedom to concentrate their use of the course according to their weekly availability, the estimated duration of the two modules is as follows:
- Module 1 Diagnostics of Longevity Medicine: 56 hours in total between teaching and exams for an estimated weekly commitment of 19 weeks
- Module 2 Longevity Medicine Therapies: 44 hours in total between teaching and exams for an estimated weekly commitment of 15 weeks
- Clinic Internship Module (optional): 80 hours of clinical practice at SoLongevity Healthcenters srl facilities, for a continuous 2-week in-person commitment.
Registration fee and organizational secretariat
The registration fee for Module 1 Diagnostics of Longevity Medicine is €2,500, for Module 2 Therapies of Longevity Medicine is €2,500, including the “clinical internship” segment.
Registering for both modules at the same time entitles you to a 10% discount overall: instead of €5,000, the total cost is €4,500.
The payment methods are structured differently depending on the student’s training selection.
In case of enrollment of only 1 module at a time, the following is expected:
- 20% deposit (€500) upon registration.
- Payment of the balance (€2,000) before starting of the module.
- This will entitle you to access the training platform.
In case of simultaneous registration for both modules, the following is expected:
- 20% deposit (€900) upon registration, on the discounted value of €4,500
- Payment of a 40% deposit (€1,800) before starting module 1. This will entitle you to receive the access credentials to the training platform.
- Payment of the balance (€1,800) before starting of module 2. This will entitle you to receive the access credentials for the second module.
Contact us for any additional information
Organized by:
In collaboration with:
ECM Office, University of Pavia.
30+30
Education credits ECM
UniPv Open Badge
High-profile Scientific Committee
30 Professors and industry experts
160 total hours asynchronous teaching
Course in English
